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A Mini-Guide On Pharmaceutical Raw Materials ...
Pharmaceutical raw materials are substances, chemicals, extracts, etc, which are the basis of manufacturing of
pharmaceutical drugs.  While some of these substances ...

Themedica » Pharmaceutical Raw Material

  Pharmaceutical Raw Material
Pharmaceutical raw materials comprise substrates or elements that are used for manufacturing different types of drugs e.g. endocrine disorder drugs, musculoskeletal system drugs, anti-infective drugs viz. cephalexin, penicillin, ampicillin, cephradine, etc. Pharmaceutical excipients and ingredients or raw materials used to manufacture drugs are extracted form different types of sources. These sources could be natural or synthetic. Recently, many of the raw materials previously derived from natural sources are being produced synthetically in part or even bio-technologically. This is so because manufacturing them artificially is economical, safer, and much quicker. Pharmaceutical raw materials are manufactured using different types of acids, alcohols, esters, phenones, pyridines, etc.

Pharmaceutical raw materials are essential to producing pharmaceutical drugs and include active pharmaceutical ingredients (API), also known as bulk active, are pharmaceutically active, and have the desired pharmacological effects on the body e.g. alvimopan, sparfloxacin, sapropterin dihydrochloride, lanreotide acetate, nicotinic acid, etc. In contrast pharmaceutical excipients are the pharmaceutically inert substances which help in delivering the active ingredient, e.g. antiadherents, binders, coatings, disintegrants, fillers, etc.
  Animal Extract  Drug Intermediate  Herbal Raw Material
  Pharmaceutical Additives  

Animal Extract
These pharmaceutical excipients and ingredients include compositions extracted out of animals as well as their cells, tissues and organs. The different varieties of animal extracts available in the market include beeswax, chitin, mushroom extract, royal gelly, shark cartilage etc. The total size of animal extract industry is approximately US $ 19.6 billion, growing at a rate of 4.7% annually.

Animal Extract Pharmaceutical Ingredients
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Royal JellyShark Cartilage 

Drug Intermediate
Drug intermediates are derivatives, substances or chemical compounds that are further used in the production or manufacture of a pharmaceutical drug. These pharmaceutical molecules are synthesized from simpler compounds and are determined to be used at the later syntheses stage of intricate products. Intermediates being invaluable to manufacturing pharmaceuticals are used to make many types of drugs including anti-allergic drugs, antineoplastic agents, anti diabetic drugs, antibiotics viz. ceftriaxone, ceftriaxone, bromhexine, cefuroxime, etc. At present, this industry approximately generates products worth US $ 8.4 billion.

Drug Intermediate Pharmaceutical Ingredients
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Acid DerivativesAlcohol DerivativesAmine Derivatives
Ester DerivativesPhenone DerivativesPyridine Derivatives

Herbal Raw Material
These pharmaceutical ingredients are extracts derived from natural sources such as flower, fruit, fungus, herbs, leaves, fungi, roots, seeds, stems etc. These pharmaceutical excipients and ingredients are used for manufacturing drugs, medicines, antiseptic creams, lotions, shampoos and other herb based products. The global market for herbal raw material is US $ 584.3 billion, which is estimated to reach US $ 225 trillion in the coming few years.

Herbal Raw Material Pharmaceutical Ingredients
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AbsorbentFlower ExtractFruit Extract
FungusHerbsLeaf Extract
Root ExtractSeed ExtractStem Extract
Pharmaceutical Additives
These are the inactive pharmaceutical ingredients used for making different types of drugs or medicines, e.g. antibiotics viz. cephalexin, amoxicillin, piperacillin, cephradine, etc. These pharmaceutical excipients include dyes, flavors, binders, emollients, fillers, lubricants, preservatives, and many more classifications. Some of the common additives available in the market are corn starch, lactose, talc, magnesium stearate, sucrose, gelatin, calcium stearate, silicon dioxide, shellac and glaze. The pharmaceutical additives have many uses such as, causing the drug to dissolve slowly, serve as binders, etc.

Pharmaceutical Additives
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Anti-Caking AgentAntifoaming AgentAntimicrobial
AntioxidantAstringentBase Additive
BioenhancerChelating AgentChitin
Citric AcidCoagulantColorant

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